Associate Director, Vector Purification & Formulation

Posted 27 March 2020
Salary Up to £0.00 per annum
LocationBedford
Job type Permanent
ReferenceBBBH101443_1585329538
Contact NameVictoria Wallace

Job description

As a Vector Purification and Formulation Lead you will support multiple therapeutic gene therapy programs by leading AAV vector purification and formulation for use in research and initial process development.

You will contribute by:
· Purification of viral vectors (AAV) - benchtop to 50L bioreactor scale
· Establish and optimize downstream processes for multiple programs
· Establish automation capability across entire gene therapy purification operations
· Responsible for purification schedule, filtration & chromatography unit operations
· Hands-on technical leadership and managerial responsibility for downstream and formulation research team
· Collaborate with upstream, analytics and vector biology teams within Gene Therapy Vector Core and Discovery, Tox and CMC teams within the greater organization
· Ability to function independently and cross functionally across various teams (medicinal chemists, cell biologists, disease area exerts, antibody engineers, etc)
· Ability to manage priorities, and engage/communicate in a multidisciplinary environment

Interested? For this position you'll need the following education, experience and skills:
Minimum Qualifications:
· Ph.D in a related science or field
· A minimum of 3 years of viral vector purification and formulation experience in industry

Preferred Qualifications:
· Biologics downstream process development and tech transfer experience in industry is a plus.
· IND and BLA filing experience for gene therapy applications is a plus.