Scientist, downstream purification

LOCATION:

Greater Boston Area

TITLE:

Sr. Scientist, Process Development

ROLE RESPONSIBILITIES:

• Perform benchtop and preparative separations of rAAV particles from suspension HEK293 cell lines using various filtration, TFF, centrifugation and chromatographic techniques
• Develop protocols for viral capsid purification using column chromatography / AKTA protein purification systems
• Complete concentration and diafiltration processes using various TFF systems
• Provide support for and lead the transfer of developed protocols and downstream processes to internal and external manufacturing parties.

CANDIDATE REQUIREMENTS:

• BS/MS in a relevant discipline
• Minimum 2 years of experience in virus (preferably AAV) production, purification, titration and transduction
• Experienced in standard molecular biology techniques

If you meet the requirements above and would like to be considered for this position, apply on-line now for immediate consideration and to be contact with further details.