Scientist I/II - Functional Genomics/Sequencing

Posted 23 March 2020
Salary Up to £0.00 per annum
Location
Job type Permanent
ReferenceBBBH101086_1585000567
Contact NameBecky Krage

Job description

COMPANY:

Global biopharmaceutical company with a focus on rare diseases.

LOCATION:

San Rafael, CA

RELOCATION ASSISTANCE:

Yes

TITLE:

Scientist I/II - Functional Genomics, Genetic Sequencing - full-time, perm

ROLE RESPONSIBILITIES:

  • Utilize iPSC cellular models and next generation sequencing technologies to advance their therapeutics research and discovery efforts
  • Maintain mammalian cell cultures, utilize gene editing technologies to develop in vitro functional models and perform high-throughput scRNA-seq on pooled genetic perturbation screens
  • Design, develop, execute and analyse experimental research projects in collaboration with cross-functional teams

CANDIDATE REQUIREMENTS:

  • PhD in a relevant, scientific field
  • Experience with hESC/hiPSC models of disease utilizing techniques such as differentiation, 2D and 3D cell culture and organoid cultures.
  • Working knowledge in genomics technology (WGS, ChIP-seq, ATAC-seq, RNA-seq, scRNA-seq) and with the use of liquid handling robotics (Hamilton, BioMEK, Tecan) for mammalian cell culture or NGS library preparation is preferred.
  • Design and execution of iPSC studies and genetic screens (ie MPRA or STARR-Seq) for target identification and MOA characterization.
  • Strong microscopy skills, including immunohistochemistry, 3D imaging, in situ hybridization, live cell imaging, and/or high content imaging.

If you meet the requirements above and would like to be considered for this position, apply on-line now for immediate consideration and to be contact with further details.

Unfortunately, there is no visa sponsorship available for this position.