Sr. Principal Scientist Vector Development

Posted 09 January 2020
Salary Up to £0.00 per annum
LocationCambridge
Job type Permanent
ReferenceBBBH97600_1578580406
Contact NameVictoria Wallace

Job description

LOCATION:

Greater Boston Area

TITLE:

Sr./Principal Scientist - Vector Development

ROLE RESPONSIBILITIES:

  • Perform benchtop and preparative separations of rAAV particles from suspension HEK293 cell lines using various filtration, TFF, centrifugation and chromatographic techniques
  • Develop protocols for viral capsid purification using column chromatography / AKTA protein purification systems
  • Complete concentration and diafiltration processes using various TFF systems
  • Provide support for and lead the transfer of developed protocols and downstream processes to internal and external manufacturing parties.

CANDIDATE REQUIREMENTS:

  • Degree in chemical engineering, biology, biochemistry, chemistry, biotechnology, or related field
  • PhD in a relevant subject matter (e.g. chromatography/filtration of biologics), with a minimum of 4 years industry experience in process development.
  • Previous experience working with protein biologics or vaccines is a must, prior experience working with rAAV products desired
  • Proficient with the use of AKTA and other chromatography systems, UF/DF systems, and cell filtration devices

If you meet the requirements above and would like to be considered for this position, apply on-line now for immediate consideration and to be contact with further details.