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Scientist I, Analytics for Gene Therapy

  • Location Boston
  • Job-type Permanent
  • Reference BBBH106752
  • Salary Up to £0.00 per annum
  • Specialisation Actuarial
  • Posted September 04, 2020

COMPANY:

Our client is a biotechnology company specializing in genetic medicine, having built a world leading pipeline for the treatment of Duchenne muscular dystrophy (DMD)

LOCATION:

Greater Columbus Ohio Area

TITLE:

Scientist I, Analytics for Gene Therapy

ROLE RESPONSIBILITIES:

  • Design and execute cell culture experiments and bioanalytical assays to support manufacturing, purification and clinical comparability of AAV gene therapy products
  • Maintain clean and fully functional cell culture laboratory and adhere to all laboratory standards as defined in SOPs
  • Design, optimize and perform analytical assays such as DNA/RNA isolation, cell transfection, qPCR, RT-qPCR, ddPCR, ELISA, SDS-PAGE and Western Blot
  • Perform high throughput qPCR assay to support AAV production processes
  • Perform AAV infectivity titration and neutralization assays

CANDIDATE REQUIREMENTS:

  • Degree in Molecular Biology, Biotechnology, Biochemistry, Immunology, Virology, or a related field
  • Ph.D. with 0-2+ or MS with 6+ years of related experience in method development and analysis using high throughput molecular biology techniques
  • Experience with aseptic techniques and mammalian cell culture systems, such as plates, flasks and bioreactors for both adherent and non-adherent cell types

If you meet the requirements above and would like to be considered for this position, apply on-line now for immediate consideration and to be contact with further details.