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Senior/Principal AAV Gene Therapy Scientist

  • Location Cambridge
  • Job type Permanent
  • Reference BBBH114505


AAV Gene Therapy start-up backed by proven investors and an experienced leadership team


Cambridge, MA


Senior/Principal Scientist, AAV Gene Therapy (title flexible and dependent on experience)


Full-time, Permanent


This individual will contribute towards the development of AAV vectors for gene therapy. The Senior/Principal Scientist will develop and lead AAV production and purification systems to produce research-grade AAV. This person will contribute to the construct and design, plasmid prep, transfection, AAV production and purification.

The role will perform various experiments to screen gene therapy drug candidates.


  • BS, MS or PhD in a relevant, scientific field with relevant industry experience
  • Hands-on experience with AAV production and purification REQUIRED
  • Extensive experience in AAV production using HEK293 cells and/or baculovirus system
  • Extensive hands-on experience with molecular biology, cell culture, transfection, infection, and cell-based assays
  • Proficient in Western, ELISA, flow, PCR and ddPCR techniques
  • Experience cloning DNA constructs in bacterial systems

If you meet the requirements above and would like to learn more about this position, apply on-line now for immediate consideration and to be contacted with further details.