Research Associate, Molecular Biology

Research Associate, Molecular Biology

We are seeking a research associate in molecular biology to plan and execute DNA assembly, viral vector production and quality control to support genetic modification of immune cells. The successful candidate will have direct hands on experience in molecular biology and cell biology and will interface between molecular biology and viral vector core teams. The position is full time and based in South San Francisco, CA.

Duties and responsibilities:

• Plan and execute cloning strategies to support genetic modification of lymphocytes
• Use in-depth knowledge of molecular biology to optimize gene delivery and engineering
• Lentiviral/Retroviral production and virus quality control
• Cell line engineering and development

Requirement:

• Extensive hands-on experience in molecular biology, viral vector preparation, virus transduction

In-depth understanding of:

• Cloning strategies
• Primer design and PCR
• DNA manipulation
• Knowledge of molecular and cellular biology. Experience with digital droplet PCR (ddPCR) is a plus.
• Proven track record that could work efficiently both independently and as part of a team.
• Must have excellent organization, planning skills, and the ability to work under timeline in a fast-paced environment. Good verbal and written communication.
• Strong motivation with a dedicated work ethic.
• A willingness to learn and adopt new experimental skills as needed is essential.
• Industry experience in Biotech or Pharma is desirable, but we will consider candidates with relevant academic experience.
• BS, or MS in Molecular Biology or related field with 0-5 years experience. Previous experience in Biotech field preferred.

DESIRED KEY COMPETENCIES

• Proficiency in vector design and cloning techniques (Golden Gate, Gibson and In-fusion assembly)
• Proficiency in sequence analysis (SnapGene and/or Vector NTi)

• Proficiency with lentiviral vectors preferred