Scientist I or II - Non-viral delivery & Gene Editing

COMPANY:

Global biopharmaceutical company with a focus on rare diseases.

LOCATION:

San Francisco Bay area

TITLE:

Scientist I/II, Non-Viral Delivery & Gene Editing (R&D Group)

TYPE:

Full-time, permanent

JOB DESCRIPTION:

The Scientist I/II, Non-Viral Delivery & Gene Editing will be a key contributor to the Genetics Research and Delivery Group. This individual will be responsible for supporting the ongoing gene therapy efforts within the Genetics Research and Delivery Group. Responsibilities include:

• Initiate, direct, and perform experiments to develop and optimize non-viral delivery methodologies using lipid nanoparticle (LNP) and/or other nanoformulations for novel genetic systems
• Develop and execute assays assessing and characterizing LNP and novel nanoparticle formulations
• Manage direct reports and collaborate with cross-functional teams and external partners

CANDIDATE REQUIREMENTS:

• PhD with 0-5+ years of experience (Scientist I = 0-2+ years of industry; Scientist II = 2-5+ years of industry experience)
• Strong background in molecular biology, cell engineering, gene, and cell therapy
• Experience with genome therapy for human therapeutics
• Experience with non-viral and viral delivery methods (such as LNP and AAV) in vitro and in vivo
• Experience with state-of-the-art molecular biology techniques: RT-qPCR, western blot, ELISA, molecular cloning, nucleic acid purification, NGS library construction

DESIRABLE SKILL SETS:

• Expertise with genome modifications for human therapeutics
• Experience working with primary and iPSC-derived cells as well as complex cell culture systems

If you meet the requirements above and would like to learn more about this position, apply on-line now for immediate consideration and to be contact with further details.